Boost your Catalyst Synthesis and Screening

Overview

Chemspeed's solution

The leading technology in overhead gravimetric dispensing / dosing (patented) combined with our versatile, fully automated SBS- / well-plate pressure block and our user-friendly software, eanble you to acceleratel, standardize and digitalize your catalyst synthesis & screening in flexible well plate formats (e.g. 12x20 mL, 24x8 mL, 48x2 mL, 96x1 mL total volume glass vials).

Workflow

Example workflow

The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.

ISYNTH CATSCREEN 96

Add catalyst

Add solvent

Shake

Add solid, liquid in vial on MTP

Transfer MTP to pressure block

Pressure

Shake, Heat (CATSCREEN)

Transfer MTP to tray

Work-up e.g. filtration, sampling

Benefits

Powerful advantages

Fully automated, integrated catalysts preparation and screening at ambient and elevated pressure in 96-well plates up to 100 bar safety pressure and 250°C jacket temperature, work-up, analysis.
Easy-to-use disposable multi-functional, high-precision glass reactor arrays (SBS- / well-plate based) - e.g. 12x20 mL, 24x8 mL, 48x2 mL, 96x1 mL total volume glass vials.
Unique fully automated well-plate based pressure screening block for reactive gas chemistries (CATSCREEN) and superheated chemistries (SPEEDCHEM).
Work-up by e.g. L/L extraction, filtration, solid-phase extraction, crystallization, and drying.
Proprietary robotic tool exchange.
Gravimetric solid handling from μg to g.
Gravimetric liquid handling from mg to g / μL to mL.
Chemistry proven liquid handling with e.g. pH, filtration, heated needle extension.
Throughput, e.g. 12 / 24 / 48 / 96 / ... parallel reactions per run based.
Sampling and various integrated analytics such as benchtop online NMR, HPLC (MS), UPLC (MS), GC (MS), UV-VIS, NIR / MIR / DLS measurement cell.
Ventilated, conditioned hood for e.g. sensitive, low-temperature chemistry (optional integration within customized MBraun glove-box).
AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface (e.g. python custom device) to e.g. LIMS, ELN, data analysis, AI / ML closed loop.
Optional integrated online benchtop NMR - including but not limited to 80 MHz Fourier RxnLite, NMR device, sample injection port, software with advanced chemical profiling and hardware integration, H / F / C / P / Si / B, 1D and 2D spectra, online data acquisition via flow cell or offline via standard 5 mm sample tubes, permanent magnet - no liquid nitrogen or helium required, 2 Gauss line inside NMR device housing

High throughput catalyst synthesis & screening in flexible well-plate formats

Chemspeed's solution

Example workflow

ISYNTH CATSCREEN 96

Powerful advantages

AUTOSUITE