High throughput organics, inorganics, polymer synthesis under superheated, accelerated conditions

ISYNTH SPEEDCHEM for superheated chemistry

Automated, parallel synthesis in verasatile 96-well plates with disposable glass vials / reactors under accelerating superheated conditions (van't Hoff rule).

Two blue chemspeed robotic platforms in metal sitting in a white hallway

Overview

Chemspeed's solution

The ISYNTH SPEEDCHEM uses a combination of elevated temperature and autogeneous pressure to dramatically increase the reaction rate, resulting in shorter reaction times and often higher selectivities for e.g. small-molecule, polymer, porous materials, cathode materials synthesis.

Workflow

Example workflow

The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.

ISYNTH SPEEDCHEM

Benefits

Powerful advantages

Fully automated, integrated synthesis elevated pressure in 96-well plates up to 100 bar safety pressure and 250°C jacket temperature, work-up, analysis.
Reagent preparation (liquids and solids), multistep synthesis, work-up, purification, analysis and product transfer to storage.
SPEEDCHEM - increased temperature to e.g. 40 °C above the boiling point results in about 16 times faster reaction at better quality, higher reagents solubility into solvent, less side reactions / reagent alteration and higher chemical yield, lower energy usage.
Easy-to-use disposable multi-functional, high-precision glass reactor arrays (SBS- / well-plate based) - e.g. 12x20 mL, 24x8 mL, 48x2 mL, 96x1 mL total volume glass vials.
Unique fully automated well-plate based pressure screening block for reactive gas chemistries (CATSCREEN) and superheated chemistries (SPEEDCHEM).
Work-up by e.g. L/L extraction, filtration, solid-phase extraction, crystallization, and drying.
Proprietary robotic tool exchange.
Gravimetric solid handling from μg to g.
Gravimetric liquid handling from mg to g / μL to mL.
Chemistry proven liquid handling with e.g. pH, filtration, heated needle extension.
Throughput, e.g. 12 / 24 / 48 / 96 / ... parallel reactions per run based.
Ventilated, conditioned hood for e.g. sensitive, low-temperature chemistry (optional integration within customized MBraun glove-box).
AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface (e.g. python custom device) to e.g. LIMS, ELN, data analysis, AI / ML closed loop.

High throughput organics, inorganics, polymer synthesis under superheated, accelerated conditions

Chemspeed's solution

Example workflow

ISYNTH SPEEDCHEM

Powerful advantages

AUTOSUITE