High output process research / chemical development / scale-up

MULTIPLANT / AUTOPLANT PRORES

Quality by design (QbD), proven accetable range (PAR) driven automated process R&D / chemical development, scale-up and preparative synthesis.

Two blue chemspeed robotic platforms in metal sitting in a white hallway

Overview

Chemspeed's solution

The Chemspeed AUTOPLANT PRORES has been designed for high output experimentation in the development and optimization of pharmaceuticals, agrochemicals, polymers, specialty chemicals, catalysts, cathode materials, photovoltaics materials, storage materials and many more.

End-to-end process R&D / chemical development / scale-up
Organic and inorganic synthesis, reactions under pressure
Preparative synthesis
Crystallization

The cutting edge Process Development Workstation technology allows scientists to execute and perform a variety of workflows in a fully automated fashion and truly mimic the final industrial production process. It provides all the flexibility to optimize integrated reaction sequences, even if a complex configuration of reactors and feed vessels is required.

Workflow

Example workflow

The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.

MULTIPLANT / AUTOPLANT PRORES

Benefits

Powerful advantages

Each reactor with its own set of conditions - individually controlled tank reactors (reactor volumes 100, 240, 1’000 mL total volume) with precise, continuous feeds:

Easily exchangeable stirrer designs (anchor, twisted blade, gas entrainment stirrers…).
Powerful mixing for viscosities up to 80 Pa.s at 300 rpm and 30 Pa.s at 900 rpm with an anchor stirrer.
Flexible and precise continuous feeds, down to 10 μL / min.
Up to 8 continuous liquid, liquefied gas and / or gas feeds per reactor and additional unlimited overhead access.
Temperature control, 0.1 °C.
Pressure up to 100 bar over the entire temperature range up to 250 °C with corresponding safety installations.
Parallel high-performance calorimetry data.
Viscosity data.
Dean Stark water trap.
Distillation bridge.
Vacuum for different purposes: inertization, crystallization, ...
PAT interfaces to various in-situ probes, for example: pH, UV-VIS, IR, Raman, PSD, calorimetry.
Measurement of gas consumption.
Extraction, filtration, evaporation, crystallization, distillation.
Reflux.
AUTOSUITE software - drag & drop experimentation with easy interface to data analysis.
Interface for e.g. DOE, ML, AI, LIMS, ELN, ERP integration.

Software

AUTOSUITE

Chemspeed’s AUTOSUITE software packages execute and control all modules in every solution. They control all Chemspeed robotic platforms and any other integrated 3^rd-party software and hardware.

Explore AUTOSUITE

Chemspeed AutoSuite Software laptop screen