SWING CRYSTAL

Crystallization, polymorph, salt and solubility screening in unique MTP blocks with bottom glass-plate for direct transfer to XRPD.

Overview

The leading technology in overhead gravimetric dispensing / dosing (patented) combined with a wide range of MTP-format crystallization plates and our user-friendly software enable you to accelerate, standardize, digitize your crystallization / polymorph screening.

Workflow

SWING CRYSTAL - Crystallization screening

Migrated workflow: SWING CRYSTAL - Crystallization screening

Workflow

SWING CRYSTAL - Cooling (crash or controlled)

Migrated workflow: SWING CRYSTAL - Cooling (crash or controlled)

Workflow

SWING CRYSTAL - Anti-solvent

Migrated workflow: SWING CRYSTAL - Anti-solvent

Workflow

SWING CRYSTAL - Evaporation (fast or slow)

Migrated workflow: SWING CRYSTAL - Evaporation (fast or slow)

Workflow

SWING CRYSTAL - Slurry

Migrated workflow: SWING CRYSTAL - Slurry

Benefits

Decrease in cost per sample up to 90+ %.
Increase in productivity by a factor of 10.
Up to 192 crystallization experiments per run can be done on MTP based and other formats.
Wide range of workflows: salt, polymorph, co-crystal, solubility screening (incl. agitation, pH, temperature gradients, filtration, controlled evaporation).
Systematically investigate the influence of critical factors such as different solvents (eluotropic series), different concentrations, rate of evaporation, temperature, cooling rate, agitation on crystal structures.
Run two different crystallization workflows simultaneously.
Highly reliable and precise gravimetric dispensing tools for liquid and solid dispensing.
Different reactor / well sizes (from < 1 mL to 100 mL in disposable formats and up to 1’000 mL in high output process development reactors) allow for screening and development / scale-up on the same platform.
Easy access to data with a convenient interface to pull results into Excel or virtually any other software.
Interface to DoE, ML, AI, LIMS, ERP.