example solution
Swing

Accelerated, standardized crystallization screening

SWING CRYSTAL
Two blue chemspeed robotic platforms in metal sitting in a white hallway
Overview

Chemspeed's solution

The leading technology in overhead gravimetric dispensing / dosing (patented) combined with a wide range of MTP-format crystallization plates and our user-friendly software enable you to accelerate, standardize, digitize your crystallization / polymorph screening. 


Workflow

Example workflows

SWING CRYSTAL - Crystallization screening

SWING CRYSTAL - Cooling (crash or controlled)

SWING CRYSTAL - Anti-solvent

SWING CRYSTAL - Evaporation (fast or slow)

SWING CRYSTAL - Slurry

Benefits

Powerful advantages

  • Decrease in cost per sample up to 90+ %.
  • Increase in productivity by a factor of 10.
  • Up to 192 crystallization experiments per run can be done on MTP based and other formats.
  • Wide range of workflows: salt, polymorph, co-crystal, solubility screening (incl. agitation, pH, temperature gradients, filtration, controlled evaporation).
  • Systematically investigate the influence of critical factors such as different solvents (eluotropic series), different concentrations, rate of evaporation, temperature, cooling rate, agitation on crystal structures.
  • Run two different crystallization workflows simultaneously.
  • Highly reliable and precise gravimetric dispensing tools for liquid and solid dispensing.
  • Different reactor / well sizes (from < 1 mL to 100 mL in disposable formats and up to 1’000 mL in high output process development reactors) allow for screening and development / scale-up on the same platform.
  • Easy access to data with a convenient interface to pull results into Excel or virtually  any other software. 
  • Interface to DoE, ML, AI, LIMS, ERP.
Software
Chemspeed AutoSuite Software laptop screen